{"id":3244,"date":"2022-09-14T09:34:20","date_gmt":"2022-09-14T07:34:20","guid":{"rendered":"https:\/\/hemerapharma.com\/risultati-preclinici\/"},"modified":"2025-08-01T17:21:50","modified_gmt":"2025-08-01T15:21:50","slug":"preclinical-results","status":"publish","type":"page","link":"https:\/\/hemerapharma.com\/en\/preclinical-results\/","title":{"rendered":"Preclinical results"},"content":{"rendered":"

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The value of an idea lies in the using of it ~ Thomas Edison<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Header” module_id=”Board-Directors” _builder_version=”4.18.1″ _module_preset=”default” background_enable_color=”off” background_image=”https:\/\/hemerapharma.com\/wp-content\/uploads\/2022\/09\/e-sfondo.png” custom_padding=”8px|0px|8px||true|” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ use_custom_gutter=”on” make_equal=”on” disabled_on=”on|on|on” _builder_version=”4.18.1″ custom_padding=”60px||60px||true|” disabled=”on” locked=”off” global_colors_info=”{}”][et_pb_column type=”1_2″ module_class=”iq-centra-verticale” _builder_version=”4.18.0″ global_colors_info=”{}”][et_pb_text _builder_version=”4.18.1″ max_width=”99.9%” module_alignment=”center” custom_margin=”||||false|false” animation_style=”fade” text_font_size_tablet=”” text_font_size_phone=”” text_font_size_last_edited=”on|tablet” text_orientation_tablet=”center” text_orientation_phone=”center” text_orientation_last_edited=”on|tablet” locked=”off” global_colors_info=”{}”]<\/p>\n

Da oltre 10 anni il gruppo di scienziati di Hemera studia e sperimenta terapie per la rigenerazione del tessuto nervoso. <\/b><\/p>\n

Nel corso degli ultimi anni, sono stati realizzati 10 esperimenti indipendenti in vivo<\/b> su 220 topi con un modello di lesione spinale severa e contusiva, che hanno portato a risultati scientificamente solidi e molto promettenti.<\/p>\n

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In un modello preclinico di lesione midollare severa, la somministrazione della terapia REMAST ha dimostrato di promuovere il riparo del tessuto nervoso danneggiato<\/strong> e ridurre gli effetti negativi indotti dalla lesione midollare, permettendo un miglioramento funzionale duraturo nel tempo<\/strong>.<\/p>\n

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For more than a decade now, Hemera\u2019s team has been studying and testing therapies for the regeneration of nervous tissue<\/strong>.<\/p>\n

Over the last few years, 21 independent in vivo experiments<\/strong> were performed on 539 mice using a model of blunt spinal cord injury, generating scientifically robust and very promising data.<\/p>\n

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In a preclinical model of severe spinal cord injury, the administration of REMAST therapy was proven to promote the repair of damaged nervous tissue<\/strong> and reduce the negative effects induced by a spinal cord lesion, allowing for long-lasting functional improvement<\/strong>.<\/p>\n

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REMAST <\/span>therapy’s<\/h2>\n

EFFECTIVENESS PROFILE<\/h1>\n

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Pre-clinical studies have shown that the therapy:<\/strong><\/p>\n

[\/et_pb_text][et_pb_blurb title=”Has a neurotrophic effect, that is, it stimulates the growth of nervous tissue and motor neurons” use_icon=”on” font_icon=”R||divi||400″ icon_placement=”left” image_icon_width=”35px” _builder_version=”4.19.5″ _module_preset=”default” header_font=”||||||||” header_text_color=”#606060″ header_font_size=”20px” width=”78.9%” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Has an anti-inflammatory action at the site of the injury” use_icon=”on” font_icon=”R||divi||400″ icon_placement=”left” image_icon_width=”35px” _builder_version=”4.19.5″ _module_preset=”default” header_font=”||||||||” header_text_color=”#606060″ header_font_size=”20px” width=”78.7%” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Remodels and reduces the scar that causes disruption of neuronal connections” use_icon=”on” font_icon=”R||divi||400″ icon_placement=”left” image_icon_width=”35px” _builder_version=”4.19.5″ _module_preset=”default” header_font=”||||||||” header_text_color=”#606060″ header_font_size=”20px” width=”78.9%” global_colors_info=”{}”][\/et_pb_blurb][et_pb_blurb title=”Has a pro-angiogenic effect, that is, it promotes the ability to create new blood vessels” use_icon=”on” font_icon=”R||divi||400″ icon_placement=”left” image_icon_width=”35px” _builder_version=”4.19.5″ _module_preset=”default” header_font=”||||||||” header_text_color=”#606060″ header_font_size=”20px” width=”79.1%” global_colors_info=”{}”][\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.18.1″ _module_preset=”default” background_color=”#eaeaea” locked=”off” global_colors_info=”{}”][et_pb_row disabled_on=”on|on|on” _builder_version=”4.18.1″ _module_preset=”default” custom_padding=”3px||3px|||” disabled=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.18.1″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.18.1″ _module_preset=”default” header_3_font=”Sarabun||||||||” header_3_text_color=”#333333″ header_3_font_size=”25px” global_colors_info=”{}”]<\/p>\n

L\u2019azione di Remast \u00e8 riferita esclusivamente al loro effetto rigenerativo benefico<\/b><\/h3>\n

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REMAST <\/span>therapy’s safety profile<\/h3>\n

In a preclinical experimental context, this therapy has shown a high safety profile:<\/p>\n

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Impostazione autologa, cio\u00e8 le cellule terapeutiche sono derivate dal paziente stesso<\/p>\n

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Nessuna manipolazione genetica, solo modifica del fenotipo<\/p>\n

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Reversione spontanea del fenotipo cellulare attivato, alcuni giorni dopo il trattamento<\/p>\n

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Autologous approach, that is, the therapeutic cells are derived from the patient himself<\/p>\n

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No genetic manipulation, just phenotype modification<\/p>\n

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Spontaneous reversal of the activated cell phenotype a few days after the treatment<\/p>\n

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No evidence of side effects in the preclinical setting, even with long-term monitoring<\/p>\n

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The value of an idea lies in the using of it ~ Thomas EdisonDa oltre 10 anni il gruppo di scienziati di Hemera studia e sperimenta terapie per la rigenerazione del tessuto nervoso. Nel corso degli ultimi anni, sono stati realizzati 10 esperimenti indipendenti in vivo su 220 topi con un modello di lesione spinale […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-3244","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/pages\/3244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/comments?post=3244"}],"version-history":[{"count":14,"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/pages\/3244\/revisions"}],"predecessor-version":[{"id":6469,"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/pages\/3244\/revisions\/6469"}],"wp:attachment":[{"href":"https:\/\/hemerapharma.com\/en\/wp-json\/wp\/v2\/media?parent=3244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}