Researchers at Hemera, including co-founders Ilaria Decimo and Francesco Bifari and senior scientist Sissi Dolci, have published a key study in STAR Protocols by Cell Press, essential for the development of REMaST®, our advanced cell therapy for nervous tissue regeneration in severe spinal cord injury. The study will appear in the 2026 print edition.
The research presents the first murine model of severe contusive-compressive spinal cord injury capable of accurately replicating the main pathophysiological features of human spinal cord injury. This model provided the rigorous preclinical foundation for generating all the data demonstrating REMaST®’s ability to promote neuronal regeneration and functional recovery.
Recognition by the international scientific community highlights the innovation and relevance of the model, reinforcing the predictive value of REMaST® for human translation and paving the way for the therapy’s upcoming translational phase.
🔗 Read the full article: Protocol to develop a preclinical severe contusive-compressive SCI mouse model for translational research